# Sermorelin References: The Cited GHRH(1-29) Literature

> The full Sermorelin reference list: every GHRH(1-29) study cited across this site, with authors, journals, DOIs, and PubMed links for verification.

Every study cited across this site, logged with DOI and PubMed identifier for independent verification.

## How to read this register

Every quantitative claim on this site maps to a numbered entry below. Each entry carries authors, journal, year, and a resolvable identifier (DOI and/or PubMed PMID) so any reader can pull the primary source. The list is intentionally the complete set of works cited — nothing on the other pages asserts a figure that does not resolve to an entry here.

## References

[1] Granata R, Leone S, Zhang X, Gesmundo I, Steenblock C, Cai R, Sha W, Ghigo E, Hare JM, Bornstein SR, Schally AV. Growth hormone-releasing hormone and its analogues in health and disease. Nat Rev Endocrinol. 2025;21(3):180-195. https://pubmed.ncbi.nlm.nih.gov/39537825/
[2] Thorner M, Rochiccioli P, Colle M, Lanes R, Grunt J, Galazka A, Landy H, Eengrand P, Shah S. Once daily subcutaneous growth hormone-releasing hormone therapy accelerates growth in growth hormone-deficient children during the first year of therapy. J Clin Endocrinol Metab. 1996;81(3):1189-96. https://pubmed.ncbi.nlm.nih.gov/8772599/
[3] Wilton P, Chardet Y, Danielson K, Widlund L, Gunnarsson R. Pharmacokinetics of growth hormone-releasing hormone(1-29)-NH2 and stimulation of growth hormone secretion in healthy subjects after intravenous or intranasal administration. Acta Paediatr Suppl. 1993;388:10-15. https://pubmed.ncbi.nlm.nih.gov/8329825/
[4] Walker RF. Sermorelin: a better approach to management of adult-onset growth hormone insufficiency? Clin Interv Aging. 2006;1(4):307-308. https://pubmed.ncbi.nlm.nih.gov/18046908/
[5] Blackman MR. Use of growth hormone secretagogues to prevent or treat the effects of aging: not yet ready for prime time. Ann Intern Med. 2008;149(9):677-9. https://pubmed.ncbi.nlm.nih.gov/18981489/
[6] Corpas E, Harman SM, Pineyro MA, Roberson R, Blackman MR. Growth hormone (GH)-releasing hormone-(1-29) twice daily reverses the decreased GH and insulin-like growth factor-I levels in old men. J Clin Endocrinol Metab. 1992;75(2):530-535. https://pubmed.ncbi.nlm.nih.gov/1379256/
[7] Baker LD, Barsness SM, Borson S, Merriam GR, Friedman SD, Craft S, Vitiello MV. Effects of growth hormone-releasing hormone on cognitive function in adults with mild cognitive impairment and healthy older adults: results of a controlled trial. Arch Neurol. 2012;69(11):1420-1429. NCT00257712. https://pubmed.ncbi.nlm.nih.gov/22869065/
[8] Bagno L, et al. New therapeutic approach to heart failure due to myocardial infarction based on targeting growth hormone-releasing hormone receptor. Oncotarget. 2015;6(13):10846-10859. https://pubmed.ncbi.nlm.nih.gov/25797248/
[9] Veldhuis JD, et al. Age and secretagogue type jointly determine dynamic growth hormone responses to exogenous insulin-like growth factor-negative feedback in healthy men. J Clin Endocrinol Metab. 2004;89(11):5542-8. https://pubmed.ncbi.nlm.nih.gov/15531509/
[10] Russell-Aulet M, et al. In vivo semiquantification of hypothalamic growth hormone-releasing hormone (GHRH) output in humans: evidence for relative GHRH deficiency in aging. J Clin Endocrinol Metab. 1999;84(10):3490-7. https://pubmed.ncbi.nlm.nih.gov/10522985/
[11] Pont L, Alechaga E, Terrero A, et al. Comparison of magnetic bead surface functionalities for the immunopurification of growth hormone-releasing hormones prior to liquid chromatography-high resolution mass spectrometry. J Chromatogr A. 2020;1631:461548. https://pubmed.ncbi.nlm.nih.gov/32971474/
[12] Granata R, Leone S, Zhang X, et al. Growth hormone-releasing hormone and its analogues in health and disease (GHRH-receptor signaling and the GH/IGF-1 axis). Nat Rev Endocrinol. 2025;21(3):180-195. https://pubmed.ncbi.nlm.nih.gov/39537825/
[13] Pedrolli F, Morello G, et al. Growth hormone-releasing hormone attenuates amyloid deposition and neuroinflammation in Alzheimer's disease models. Cell Death Dis. 2026;17:08699. https://pubmed.ncbi.nlm.nih.gov/41946684/
[14] Vittone J, Blackman MR, Busby-Whitehead J, et al. Effects of single nightly injections of growth hormone-releasing hormone (GHRH 1-29) in healthy elderly men. Metabolism. 1997;46(1):89-96. https://pubmed.ncbi.nlm.nih.gov/9005976/

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A near-monochrome instrument reading of the sermorelin record — the GHRH(1-29) pulse traced from receptor to IGF-1 and each figure logged to its study, the body-composition data attributed to tesamorelin where it belongs and the silence where the adult anti-aging evidence runs out left unfilled; no clinic behind the console and nothing here compounded, dosed, or sold.